Dehalogenase enzymes are specialised biocatalysts that mediate the removal of halogen atoms from organic compounds, a reaction known as dehalogenation. This process is critical for environmental ...

Enzymes are vital to metabolism and drive countless biological processes in humans, plants, and industry. Yet, when overwhelmed by excess substrate, some enzymes slow down — a phenomenon known as ...

Neurodegenerative disorders are pressing global health challenges that stem from progressive neuronal dysfunction and loss. While the central roles of ...

The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to ...

A mechanism that could help scientists harness enzymes for use in drug discovery has been discovered in a research breakthrough at the University of Birmingham. In a study published in Science ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary hearing loss and neurological disease. Researchers at the Department of Cell and ...

New obesity drugs could be inspired by discovery of an enzyme that controls both weight gain and cholesterol levels in animal ...

Burkholderia pseudomallei is considered one of the most dangerous bacterial pathogens in the tropics. The disease melioidosis, caused by these ...

Nicotiana benthamiana plants in a lab at UC Davis. Plants form new branches when a hormone called strigolactone breaks down. UC Davis plant biologists have now defined the enzymes that break down ...

"Our research positions the enzyme SIRT6 as a critical and primary drug target to combat degenerative brain pathology," Toiber said. "These findings change the way we understand the relationship ...