A critical cGMP requirement is the establishment of controls to ensure quality and safety of investigational drug products, 9 including comprehensive quality systems that apply to all aspects of ...

The use of engineered viruses to deliver transgenes for therapeutic effect is wide-ranging. Contemporary gene therapy vectors based on RNA viruses such as γ-Retroviruses and Lentiviruses 1,2, and DNA ...

Viral vectors dominate gene therapy, with lentivirus, adenovirus, and AAV being key players, each with unique advantages and limitations. Non-viral vectors, such as lipid nanoparticles and GalNAc, ...

When you think of a vector, many people probably call up Vector's definition (from Despicable Me). He says: It's a mathematical term. A quantity represented by an arrow with both direction and ...

This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore tissues and organs damaged ...