In addition to improving expression levels by the inclusion of NS4A or mRNA amplification by the SFV replicase, the immunogenicity of NS3 may possibly be improved by alternative modifications. One ...

Codon-optimization describes gene engineering approaches that use synonymous codon changes to increase protein production. It is used extensively for expressing recombinant protein drugs, gene therapy ...

A study conducted by researchers at Ohio State University and the New York University Grossman School of Medicine in the USA, has revealed that optimization of codon for bacterial expression causes ...