这篇研究聚焦于结核病（TB）和非结核分枝杆菌（NTM）感染的诊断难题。通过对比多种检测方法，发现核酸基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）在鉴定分枝杆菌种类和结核分枝杆菌（MTB）耐药性方面优势显著，对指导临床治疗意义重大。 结核病与非 ...

在临床微生物诊断中，MALDI-ToF MS 技术用于细菌鉴定，但商用数据库对高致病性细菌（HPB）覆盖不足。研究人员开发相关协议并构建数据库。该数据库含 11,055 条光谱，涉及众多菌株和物种，有助于提升 HPB 诊断水平。 在医学微生物学领域，准确鉴定细菌对于疾病 ...

Matrix‐assisted laser desorption/ionisation time‐of‐flight mass spectrometry (MALDI‐TOF MS) has transformed fungal identification by offering rapid, cost‐effective and highly accurate species ...

Using MALDI-TOF, researchers can quickly and accurately determine polymer, protein and nucleic acid masses. They can also analyze and resolve complex assortments of smaller peptides and ...

Until recently, clinical diagnostic laboratories predominantly relied on conventional phenotypic ways of diagnosing infections, and sometimes on gene sequencing techniques. The latest advancements in ...

The practice of laboratory clinical microbiology is finally changing driven by the assimilation of newer technologies, like Matrix Assisted Laser Desorption Ionization - Time of Flight/Mass ...

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A new method for identifying bacteria that cause urinary tract infections (UTIs) will lead to much faster, more effective treatment as well as a reduction in costs. The procedure, described in the ...

Faster, more effective treatment and a reduction in costs can be expected by implementing a new method for identifying bacteria that cause urinary tract infections (UTIs). The procedure, described in ...

Tissue imaging is a promising technique that allows scientists to follow the distribution patterns derived from drug treatment (precursor drug and metabolites) in specific tissues or their ...