When RNA malfunctions, it can result in cancer and developmental disorders. Our cells have molecular “machines” that keep RNA “in check” and eliminate RNAs at the right time. Most come equipped with a ...

Thought LeadersEbbe Sloth Andersen, Ph.D.Associate Professor, iNANOAarhus University In this interview, AZoNano speaks with Associate Professor Ebbe Sloth Andersen from Aarhus University about a new ...

microRNAs (miRNA) are recently discovered, short segments of RNA, which play vital roles in health and disease. microRNA over- or under-abundance can switch critical disease genes on or off, ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

Shape Therapeutics, a Seattle preclinical stage biotech company developing RNA editing and gene therapy technologies, has raised $112 million. The company’s RNA editing technologies are spun out of ...

La Jolla, CA--The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape--and biologists are taught that defined shape dictates the ...

A new study shows how one of Ebola virus's key proteins, VP40, uses molecular triggers in the human cell to transform itself into different tools for different jobs. The human genome contains the ...

Noncoding RNA folds into intricate shapes that determine its function, but the rules of nucleotide patterns that determine these shapes are largely unknown. Now, an online game that tasks users to ...

Shape Therapeutics has raised $112 million in series B financing to further develop RNA editing and gene-therapy technologies. Shape’s RNA editing technology takes advantage of an enzyme called ADAR ...

Roche has agreed to license Shape Therapeutics’ RNA-editing technology in a deal worth up to $3 billion. Shape uses adeno-associated viruses to deliver RNA-editing machinery to treat neurological and ...