The Week 6 NFL schedule for the 2022 season is stacked with great matchups, and we got you covered with what you need to know heading into the weekend. Our NFL Nation reporters bring us the biggest keys to every game and a bold prediction for each matchup.

Enter the free NFL Week 18 Super 6 Contest for a chance to win cash prizes! And don't worry — Chris 'The Bear' Fallica is here to help.

Must-win AFC North and NFC South showdowns? No. 1 seeds on the line? We have picks, predictions, stats and what's at stake for every Week 18 game.

Despite its stellar record, Denver is only 6-9-1 against the spread. Los Angeles is 8-7-1 ATS but had four straight covers before losing to the Texans at home in Week 17. The Chargers are 6-9-1 to the Over while the Broncos are 7-9 to the Over.

NFL Week 18 odds, picks, predictions, TV channel, streaming information for Saturday football game between Seattle Seahawks and San Francisco 49ers.

Preview the Atlanta Falcons' NFL week 18 matchup with the Saints, including betting odds, tips, trends, and game information.

The Texans finish the regular season at home with an outside chance to win their third straight AFC South title.