Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

The Ocean Genome Legacy Center and other biorepositories like it are increasingly crucial to climate change research as ...

PHILADELPHIA — Deep in the mangrove swamps of the Caribbean lives a giant bacterium with a surprise trick for organizing its DNA. Thiovulum imperiosus wraps its genetic material in membranous fingers, ...

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable bacterial product causes mutations in DNA that have been linked to ...

The microbial toxin colibactin has just the right shape to snuggle up to DNA — but its embrace is unfortunately more cancerous than cozy. Colibactin is produced by bacteria in the gut and causes ...

Amsbio has introduced SoluLyse™, a reagent designed for efficient extraction of soluble proteins from bacterial cells. Based on a non ionic detergent formulation, SoluLyse™ perforates bacterial cell ...

A single molar from a steppe mammoth that died about 1.1 million years ago in northeastern Siberia has preserved tiny fragments of bacterial DNA. The tooth, found near the Adycha River in Russia, lets ...

Who are the real mutants, and what’s going to cure them? Of course, we all are mutants – not just as the Homo sapiens sapiens limited-edition model from 4.5 billion years of mutation at Terrestrial ...

Penn State scientists uncovered an ancient bacterial defense where dormant viral DNA helps bacteria fight new viral threats. The enzyme PinQ flips bacterial genes to create protective proteins that ...

Genetic material pulled from 13 teeth found in a grave in Lithuania revealed infectious diseases that felled the French emperor’s troops as they withdrew from Russia. By Gina Kolata Napoleon’s army ...