Base and nucleotide excision repair (BER and NER) pathways are normally associated with removal of specific types of DNA damage: small base modifications (such as those induced by DNA oxidation) and ...

William is a writer for GameRant who has been helping players solve problems for years. Don't know how to find that item or defeat that boss? He's got your back. To think, it all started with Sega's ...

Ewan Selmes is a games and entertainment journalist with several years' experience in the industry, writing for a variety of digital publications as well as small businesses. As a gamer, Ewan has more ...

aDepartment of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China bDepartment of ...

A researcher has made a discovery that alters our understanding of how the body's DNA repair process works and may lead to new chemotherapy treatments for cancer and other disorders. Researchers ...

1University Hospitals Seidman Cancer Center, Cleveland, Ohio. 2Case Western Reserve University, Cleveland, Ohio. *Correspondence Author: Tithi Biswas, Department of Radiation Oncology, Seidman Cancer ...

Translesion synthesis (TLS) is a highly conserved mutagenic DNA lesion tolerance pathway, which employs specialized, low-fidelity DNA polymerases to synthesize across lesions. Current models suggest ...

DNA repair pathways exist to correct molecular damage caused by internal and external factors. However, any damage to these pathways can result in the creation of tumors and specific types of cancers.

The ongoing fight of science against cancer has made great strides, but cancer cells have not made it easy. The complexity of cancer cells and their adaptive evolutionary nature complicate the search ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Optimal DNA damage response is associated with ...